Mini IVF: What is it?
Protocol and Costs

Starting your fertility journey can be both exciting and overwhelming, especially with so many treatment options available. If you’re exploring more gentle and cost-effective alternatives to standard IVF, Mini IVF might be a perfect choice for you. This page will guide you through what Minimal stimulation IVF entails, its benefits, and how it compares to conventional IVF, helping you make an informed decision.
What is Mini IVF?
Mini IVF, also called minimal stimulation IVF, is a reproductive procedure that uses lower doses of fertility medications compared to conventional IVF methods. The goal is to retrieve fewer but high-quality eggs during a single menstrual cycle, reducing medication use and side effects. This approach focuses on simplicity over quantity, making it a suitable option for women with specific fertility issues or those seeking a less invasive treatment.Unlike standard IVF, this treatment is designed to align more closely with natural cycles. It’s an appealing option for women who wish to avoid the intensive hormone stimulation typical of conventional IVF protocols.
Mini IVF vs IVF
- Medication Use: Minimal stimulation protocols involve oral medications and fewer injectable drugs, whereas standard IVF typically relies on higher doses of injectables
- Egg Retrieval: The goal is to retrieve a smaller number of mature eggs, focusing on quality, while traditional IVF often aims for a higher egg yield
- Cost: Costs for Mini IVF are generally lower compared to conventional approaches, making it an accessible option for many patients
- Side Effects: Reduced medication use significantly lowers the risk of ovarian hyperstimulation syndrome (OHSS), a condition where the ovaries become swollen and painful due to excessive hormone stimulation. Symptoms can range from bloating and nausea to severe abdominal pain and fluid accumulation, sometimes requiring medical intervention, offering a safer option for certain patients
Who Might Benefit from Mini IVF?
This fertility treatment is a great choice for:- Women over 40 seeking a less intensive approach
- Patients with diminished ovarian reserve who may not respond well to high doses of fertility drugs
- Individuals looking to minimize side effects or avoid risks like OHSS
- Women considering fertility preservation with a focus on quality eggs
- Those who prefer a treatment option closer to natural cycles
Mini IVF After Tubal Ligation
Mini IVF after tubal ligation provides an effective alternative for women who have had their fallopian tubes tied and want to conceive without undergoing reversal surgery. This treatment bypasses the fallopian tubes by focusing on retrieving and fertilizing high-quality eggs in a laboratory, providing a safe and effective option for conception.
Mini IVF Costs
One of the major benefits of Mini IVF is its affordability compared to standard IVF. At our fertility clinic the cost of a Mini IVF cycle is typically less than $10,000 per cycle and we offer discounts when purchasing multi-cycle packages. Medications for this procedure are also less expensive due to the reduced dosage.We are committed to making fertility treatments accessible by offering transparent pricing and personalized guidance on financial assistance options. Schedule a consultation to learn more about costs and available plans.Mini IVF Success Rates
Success rates for this approach depend on factors such as age, overall health, and specific fertility issues. While this procedure may have lower pregnancy rates than standard IVF for some patients, it remains an effective option for many, especially those with diminished ovarian reserve or women over 40.
Factors Influencing Success Rates
- Number and quality of eggs retrieved
- Age and ovarian reserve
- Quality of embryos produced during the cycle
Challenges and Considerations for Patients Over 40
Mini IVF over 40 provides a tailored approach for women in this age group, focusing on egg quality rather than quantity. This approach reduces the physical and emotional strain often associated with traditional IVF protocols. However, there are unique factors to consider:- Success rates may be lower compared to younger patients, as age significantly impacts egg and embryo quality
- The consideration of donor eggs might be a recommended option for achieving higher success rates, depending on individual circumstances
- Due to the retrieval of fewer eggs, the number of embryos available for transfer or freezing might be limited
Mini IVF Protocol: What to Expect
The Mini IVF process involves fewer medications, and a simpler timeline compared to standard IVF. Here are the typical steps:- Initial Consultation: Our fertility specialists will assess your medical history and fertility issues to create a tailored Mini IVF plan.
- Ovarian Stimulation: You’ll take oral medication and minimal doses of injectable medications to stimulate the growth of a few quality eggs
- Monitoring: Serial ultrasounds and blood tests track your response to the medication
- Egg Retrieval: Mature eggs are retrieved during a simple outpatient procedure
- Fertilization: The retrieved eggs are fertilized in the lab to create embryos
- Embryo Transfer: One or two embryos are transferred to the uterus, aiming to achieve pregnancy

Benefits and Drawbacks of Mini IVF
Benefits
- Lower use of medication reduces physical and emotional strain
- Patients can easily tolerate multiple MINI-IVF cycles
- Eggs are collected over multiple cycles to maximize success
- More affordable compared to traditional IVF
- Fewer side effects, making the process less invasive
Drawbacks
- Fewer eggs retrieved may require multiple cycles
- Success rates can be lower for some patients compared to standard IVF
